First of all, I apologize my lack of skills to write correctly in English. I've been using an MBOX with PT LE 6.1 in a very stable manner in my G4/800 768 Mb, MacOS X (10.2.6) since it is release. After several hours in the iTunes session yesterday I closed it and tryed to open the PT LE 6.1 to make a voice-over session in my studio but now it insist no to function. Every attempt is followed with the message: "another application is already using the Digidesign hardware -1133" and "could not complete your request because: MIDI filter". There is no similar or possible application opened at the same time. I've trying to figure it out with no success. Right before notice the problem the last thing that I did was to install a new program called StickyBrain that Apple's .Mac service is offering to subscribers on their site. I already unistall it. Also I take the followed steps: restart on System 9 to make the recording session with the PT LE 5.2.1 and it runs smoothly, in fact in a very fast way. So I turn again to the MacOS X to reopened the PT LE 6.1 but it fails. So, I decide to run the update combo installer of the MacOS 10.2.6 and on the fly I also reinstall the the Digidesign Core Audio 1.2, recheked the whole system, unpluged the USB cable and nothing. BTW, I do not have any MIDI port in use or a piece of equipment pluged into it. Can you help me? Sincerely, Silvio Vasconcellos